基因组编辑
清脆的
遗传增强
精密医学
Cas9
个性化医疗
转化式学习
基因组
疾病
计算生物学
医学
生物
生物信息学
基因
遗传学
心理学
病理
教育学
作者
Aniruddha Sen,Vijay Singh,Shailendra Dwivedi,Ruchika Agrawal,Akash Bansal,Shashank Shekhar,Sudhir S. Kushwaha
标识
DOI:10.2174/0115665232347734250211074241
摘要
Abstract: Gene therapy and genome editing have emerged as transformative approaches in the management of a diverse range of genetic and acquired diseases. This evaluation offers a thorough examination of the present state and prospects of these innovative technologies. Gene therapy is a prospective approach to the treatment and prevention of a variety of conditions, including complex cancers and inherited genetic disorders, which entail the introduction, removal, or modification of genetic material within a patient's cells. Genome editing, particularly through techniques such as CRISPR-Cas9, enables targeted corrections of genetic defects and opens new possibilities for personalized medicine by allowing for precise modifications at the DNA level. The review addresses the ethical implications, clinical applications, and significant advancements of these technologies. This article endeavors to underscore the substantial influence of gene therapy and genome editing on contemporary medicine by assessing the most recent research and clinical trials, thereby emphasizing their potential to revolutionize disease treatment and management.
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