Elucidating the Biosynthetic Pathway and Mechanisms of Retrochalcones

. Moreover, we determined the crystal structure of GinKR1 and identified a critical α10 helix responsible for its regioselectivity. With this α10 helix as a marker, we further discovered homologous genes of GinKR1 from 185 plant species. This study elucidates the biosynthetic pathway and underlying mechanisms of retrochalcones.