nBu4NI-Mediated oxidation of methyl ketones to α-ketoamides: using ammonium, primary and secondary amine-salt as an amine moiety

Presented is the first example of synthesizing an array of primary-, secondary-, and tertiary-α-ketoamides in moderate to excellent yields with a catalyst nBu₄NI from methyl ketones and amine/ammonium salts under mild conditions using oxidant TBHP.