生物
核型
染色体
细胞遗传学
卵巢
荧光原位杂交
癌症研究
作者
Tanja Pejovic,Sverre Heim,Nils Mandahl,Ulla Maria Flodérus,Helena Willén,Felix Mitelman
出处
期刊:Cancer Genetics and Cytogenetics
日期:1990-05-01
卷期号:46 (1): 65-69
被引量:14
标识
DOI:10.1016/0165-4608(90)90009-y
摘要
Cytogenetic analysis of short-term cultures initiated from an ovarian malignant mixed mesodermal tumor yielded the following karyotype: 59-61, XX,t(1;?)(p36;?), +t(1;9) (q43;q21), +t(2;?)(p25;?), +i(5p), +i(5p), +7, +t(7;?)(p13;?), +8,der(11) (pter----cen----q23::q13----q23::q13----q23::?), +12, + der(13)t(13;15)(q21;q15), -15,der(16) (16qter----cen----16p13::hsr::8q21----8qter), +19, + der(20)t(X;20)(q13;p13), -22, +4 - 6mar. Because the only other cytogenetically characterized ovarian neoplasm of this rare histopathologic subtype also had a small metacentric marker interpreted as an isochromosome for the short arm of a B-group chromosome, we suggest that i(5p) constitutes a nonrandom anomaly in mixed mesodermal tumors.
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