医学
彭布罗利珠单抗
内科学
肺癌
化疗
肿瘤科
PD-L1
癌症
免疫疗法
作者
Luis Paz‐Ares,Alexander Luft,David Vicente,Ali Tafreshi,Mahmut Gümüş,Julien Mazières,Bárbara Hermes,Filiz Çay Şenler,Tibor Csőszi,Andrea Fülöp,Jerónimo Rafael Rodríguez‐Cid,Jonathan Wilson,Shunichi Sugawara,Terufumi Kato,Ki Hyeong Lee,Ying Cheng,Silvia Novello,Balázs Halmos,Xiaodong Li,Gregory M. Lubiniecki
标识
DOI:10.1056/nejmoa1810865
摘要
In patients with previously untreated metastatic, squamous NSCLC, the addition of pembrolizumab to chemotherapy with carboplatin plus paclitaxel or nab-paclitaxel resulted in significantly longer overall survival and progression-free survival than chemotherapy alone. (Funded by Merck Sharp & Dohme; KEYNOTE-407 ClinicalTrials.gov number, NCT02775435 .).
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