The effects of S2-2, S2-3,S2-4,and A3 on clearing superoxide anion radical and hydroxyl radical have been studied on the paper. The results showed that all four principles had scavenging effects on superoxide anion radical and on hydroxyl radical. The intensities of the scavenging effects were relative to the molecular weight .The lower the molecular weight of agar was, the stronger the intensity of scavenging was. The intensity of the scavenging effects on superoxide anion radical was weaker than on hydroxyl radical specially. The intensity of the scavenging effect of A3 on hydroxyl radical was far stronger than that of the active control: thiourea.