In this paper,we discussed on solubilization of microemulsions composed of methyl salicylate(heptane),Tween 80(Tween 60),alcohol and water by titration. The microemulsions region and liquid crystal region were obtained by pseudo-ternary phase diagrams. We could draw a conclusion that microemulsion solubilization was effected with both the total amount of surfactant and cosurfactant on the interfacial film of microemulsion and confusable degree of interfacial film of microemulsion.