Rh( iii )-catalyzed base-free α-arylation of iodonium ylides with arylboronic acids: modular synthesis of 5-aryl barbituric acids

The first Suzuki-type cross-coupling of iodonium ylides to access medically important 5-aryl barbituric acids has developed. This general approach exhibits mild reaction conditions, operational simplicity, and robustness against moisture and air.