The Extraordinary Phenotypic and Genetic Variability of Retinal and Macular Degenerations: The Relevance to Therapeutic Developments

Isabelle Audo1,2, Marco Nassisi1,3,4, Christina Zeitz1 and José-Alain Sahel1,2,5 1Sorbonne Université, INSERM, CNRS, Institut de la Vision, Paris 75012, France 2Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts, National Rare Disease Center REFERET and INSERM-DGOS CIC 1423, Paris F-75012, France 3Department of Clinical Sciences and Community Health, University of Milan, Milan 20122, Italy 4Ophthalmology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, Milan 20122, Italy 5Department of Ophthalmology, University of Pittsburgh Medical School, Pittsburgh, Pennsylvania 15213, USA Correspondence: isabelle.audo{at}inserm.fr