调节器
软骨细胞
骨关节炎
下调和上调
软骨
突变
突变体
生物
细胞生物学
内分泌学
内科学
基因
遗传学
医学
病理
解剖
替代医学
作者
Huanhuan Liu,Anupama Binoy,Siqi Ren,T. Martino,Anna E. Miller,Craig R. G. Willis,Shivakumar R. Veerabhadraiah,Joanna Bons,Jacob Rose,Birgit Schilling,Michael J. Jurynec,Shouan Zhu
摘要
We found that Sirt5-mediated MaK is an important regulator of chondrocyte cellular metabolism, and dysregulation of Sirt5-MaK could be an important mechanism underlying aging- and obesity-associated OA development.
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