糖生物碱
保健品
龙葵
健康福利
食品科学
萃取(化学)
食品工业
生物技术
化学
传统医学
生物
植物
茄科
医学
色谱法
生物化学
基因
作者
Vincenzo Piccolo,Arianna Pastore,Maria Maisto,Niloufar Keivani,Gian Carlo Tenore,Mariano Stornaiuolo,Vincenzo Summa
出处
期刊:Foods
[MDPI AG]
日期:2024-01-20
卷期号:13 (2): 331-331
标识
DOI:10.3390/foods13020331
摘要
Unripe tomatoes represent an agri-food waste resulting from industrial by-processing products of tomatoes, yielding products with a high content of bioactive compounds with potential nutraceutical properties. The food-matrix biological properties are attributed to the high steroidal glycoalkaloid (SGA) content. Among them, α-tomatine is the main SGA reported in unripe green tomatoes. This review provides an overview of the main chemical and pharmacological features of α-tomatine and green tomato extracts. The extraction processes and methods employed in SGA identification and the quantification are discussed. Special attention was given to the methods used in α-tomatine qualitative and quantitative analyses, including the extraction procedures and the clean-up methods applied in the analysis of Solanum lycopersicum L. extracts. Finally, the health-beneficial properties and the pharmacokinetics and toxicological aspects of SGAs and α-tomatine-containing extracts are considered in depth. In particular, the relevant results of the main in vivo and in vitro studies reporting the therapeutic properties and the mechanisms of action were described in detail.
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