People pay attention to styrene-acrylic latex day by day because of its excellent chemical and physical properties. Some properties of styrene-acrylic latex can be improved through emulsion polymerization of the styrene-acrylic latex added nano-TiO2 modified by silane coupling agent. This design adopted the method of preparing emulsion, the reaction time and temperature were determined according to single factor experiment on the base of principium experiment, the optimum condition and formulation were determined according to the orthogonal experiment.