Reductive alkenylation of tertiary amides with alkenylchlorozirconocenes and alkenylboronic acids: a new approach to α-branched ( E )-allylic amines

We report a novel reagent-controlled stereoselective approach to α-branched ( E )-allylic amines via reductive alkenylation of tertiary amides using in situ -generated ( E )-alkenylchlorozirconocenes or commercially available ( E )-alkenyl boronic acids.