清晨好,您是今天最早来到科研通的研友!由于当前在线用户较少,发布求助请尽量完整的填写文献信息,科研通机器人24小时在线,伴您科研之路漫漫前行!

Evaluation of Blood Clot, Platelet-rich Plasma, Platelet-rich Fibrin, and Platelet Pellet as Scaffolds in Regenerative Endodontic Treatment: A Prospective Randomized Trial

富血小板纤维蛋白 富血小板血浆 医学 根管 牙科 纤维蛋白 血小板 射线照相术 随机对照试验 臼齿 外科 内科学 免疫学
作者
Ayça Tuba Ulusoy,Irem Turedi,Muge Cimen,Zafer C. Çehrelį
出处
期刊:Journal of Endodontics [Elsevier]
卷期号:45 (5): 560-566 被引量:108
标识
DOI:10.1016/j.joen.2019.02.002
摘要

Introduction Regenerative endodontic procedures (REPs) using autologous platelet concentrates as scaffolds can improve the biologic outcome of treatment. This prospective, randomized trial compared the clinical and radiographic performance of REPs using platelet-rich plasma (PRP), platelet-rich fibrin (PRF), a platelet pellet (PP), and an induced blot clot (BC). Methods Sixty-seven healthy children (aged 8–11 years) with 88 immature necrotic incisors were included. After the root canal disinfection step, the teeth were randomly assigned into 1 of the following groups (n = 22/group) according to the scaffold used: PRP, PRF, PP, and BC. In the PRP, PRF, and PP groups, the platelet concentrates were introduced into the root canal without prior induction of apical bleeding. Treatment outcomes were assessed using a combined clinical and radiographic scoring system, whereas the changes in root dimensions were compared using linear measurements of root length and width with ImageJ (National Institutes of Health, Bethesda, MD) and Turboreg (Biomedical Imaging Group, Swiss Federal Institute of Technology, Lausanne, Switzerland) and planar measurements using the radiographic root area (RRA) and radiographic canal area (RCA) techniques. One-way analysis of variance, the Duncan multiple range test, the Kruskal-Wallis test, the Mann-Whitney U test, and chi-square dependency tests were used for statistical analysis of data (all P = .05). Results Except for 2 teeth in the PRF and BC groups, all teeth showed similar and high success scores (periapical healing, radiographic root development, and positive response to sensitivity tests) after an average follow-up time of 28.25 ± 1.2 months. Of all teeth, 73.9% showed complete apical closure with similar closure rates among groups (P > .05) and a greater tendency for conical-shaped apical closure than a blunt apex. Although linear measurements indicated a similar increase in root length and width among all groups (P > .05), the RRA of the BC group was significantly greater than those of the PRF and PP groups, and the RCA of the BC group was significantly greater than PRP, PRF, and PP (all P < .05) when the follow-up time was not used as a factor. Eighty-six percent of the teeth showed a positive response to sensitivity tests with similar initial response times (P > .05). Conclusions PRP, PRF, and PP can yield similar clinical and radiographic outcomes to BC without the need for prior apical bleeding and with significantly less tendency for root canal obliteration. RRA and RCA may reveal minor differences that cannot be determined by linear measurements.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
张颖完成签到 ,获得积分10
3秒前
欢呼的茗茗完成签到 ,获得积分10
10秒前
丹妮完成签到 ,获得积分10
11秒前
17秒前
longlonglong完成签到,获得积分10
21秒前
23秒前
荔枝波波加油完成签到 ,获得积分10
28秒前
Danny完成签到 ,获得积分10
39秒前
Young完成签到 ,获得积分10
41秒前
郑先生完成签到 ,获得积分10
58秒前
郑志凡完成签到 ,获得积分10
59秒前
wanci应助科研通管家采纳,获得10
1分钟前
啥也不是完成签到,获得积分10
1分钟前
双眼皮跳蚤完成签到,获得积分10
1分钟前
kehe!完成签到 ,获得积分0
1分钟前
霸霸斌完成签到 ,获得积分10
1分钟前
gmc完成签到 ,获得积分10
2分钟前
谷子完成签到 ,获得积分10
2分钟前
数乱了梨花完成签到 ,获得积分10
2分钟前
寒战完成签到 ,获得积分10
2分钟前
沐浠完成签到 ,获得积分10
2分钟前
salty完成签到 ,获得积分10
2分钟前
桐桐应助123采纳,获得10
3分钟前
Shandongdaxiu完成签到 ,获得积分10
3分钟前
HCKACECE完成签到 ,获得积分10
3分钟前
Vicky完成签到 ,获得积分10
3分钟前
3分钟前
丰富的绮山完成签到,获得积分10
3分钟前
烟花应助科研通管家采纳,获得30
3分钟前
Akim应助科研通管家采纳,获得30
3分钟前
123发布了新的文献求助10
3分钟前
段采萱完成签到 ,获得积分10
3分钟前
Ava应助123采纳,获得30
3分钟前
leng完成签到 ,获得积分10
3分钟前
dragonhmw完成签到 ,获得积分10
3分钟前
烟花应助依居采纳,获得10
3分钟前
玉一一完成签到 ,获得积分10
3分钟前
哈拉斯完成签到,获得积分10
3分钟前
3分钟前
依居发布了新的文献求助10
4分钟前
高分求助中
좌파는 어떻게 좌파가 됐나:한국 급진노동운동의 형성과 궤적 2500
Sustainability in Tides Chemistry 1500
TM 5-855-1(Fundamentals of protective design for conventional weapons) 1000
Cognitive linguistics critical concepts in linguistics 800
Threaded Harmony: A Sustainable Approach to Fashion 799
Livre et militantisme : La Cité éditeur 1958-1967 500
氟盐冷却高温堆非能动余热排出性能及安全分析研究 500
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3052644
求助须知:如何正确求助?哪些是违规求助? 2709863
关于积分的说明 7418252
捐赠科研通 2354395
什么是DOI,文献DOI怎么找? 1246007
科研通“疑难数据库(出版商)”最低求助积分说明 605951
版权声明 595921