单色
波长
光学
医学
可见光谱
豚鼠
眼科
玻璃体腔
折射误差
视力
物理
内科学
作者
Qin Long,Donghong Chen,Ren-yuan Chu
标识
DOI:10.3109/15569520903178364
摘要
The purpose of this study was to determine whether long-wavelength light (760 nm) promotes myopic shift in newborn guinea pigs during eye development. Newborn guinea pigs were raised in different types of illumination: long-wavelength light, mixed-wavelength light, and normal light. The guinea pigs that received long-wavelength light were raised in the illumination of long-wavelength light for 4 weeks and in the illumination of mixed light for another 2 weeks. The other animals were raised in the illumination of mixed light or normal light for 6 weeks. All the animals had measurements of refractive status and biometric parameters before and 2, 4, and 6 weeks after being raised in the illumination. Guinea pigs raised in long-wavelength light illumination developed a significant myopia, compared with those raised in mixed-light illumination after 4 weeks. Two weeks of recovery eliminated the refractive differences between the long-wavelength group and the mixed-light group. Compared with the guinea pigs raised in normal conditions, the guinea pigs raised in long-wavelength and mixed lights were more myopic and also showed longer vitreous chamber depth at 2, 4, and 6 weeks. These data suggest that illumination with monochromatic long-wavelength light may lead to myopia and to an abnormal visual experience in newborn pigmented guinea pigs.
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