化学
磺酰
键裂
劈理(地质)
立体化学
药物化学
有机化学
催化作用
断裂(地质)
工程类
岩土工程
烷基
作者
Hui Liang,Qian Liu,Xueyan Zhao,Tianyu He,Jinyue Luo,Shenlin Huang
标识
DOI:10.1002/ejoc.202400391
摘要
Abstract A simple protocol for amide bond construction using β‐keto sulfonyl fluorides (BKSFs) as the acyl surrogates has been achieved. The reaction of BKSFs with a range of amines could be performed in presence of N ‐bromosuccinimide (NBS), affording various amides with diverse functionalities. Preliminary mechanistic studies revealed that the dibromo‐substituted sulfonyl fluorides could be the key intermediate in this amidation process.
科研通智能强力驱动
Strongly Powered by AbleSci AI