座囊菌纲
真菌
抗菌活性
内生菌
植物
生物
微生物学
子囊菌纲
化学
细菌
生物化学
遗传学
基因
作者
Lusheng Wang,Shikun Zong,Haotian Wang,Chengzhu Wu,Guangwei Wu,Feng Li,Guihong Yu,Dehai Li,Meilin Zhu
标识
DOI:10.1021/acs.jnatprod.2c00776
摘要
Four new bisanthraquinones, dothideomins A-D (1-4), were identified from Dothideomycetes sp. BMC-101, an endophytic fungus isolated from Magnolia grandiflora L. leaves. Their chemical structures were established by NMR analysis, single-crystal X-ray crystallography, and ECD analysis. Dothideomins A-D (1-4) were characterized by an unusual 6/6/6/5/6/3/6/6 octocyclic scaffold (1 and 2) and a 6/6/6/5/6/6/6 heptacyclic scaffold (3 and 4), respectively. All compounds, especially 1 and 3, exhibited potent antibacterial activity with MIC values ranging from 0.4 to 0.8 μg/mL.
科研通智能强力驱动
Strongly Powered by AbleSci AI