骨髓
髓系白血病
化疗
医学
肿瘤微环境
白血病
癌症研究
免疫学
内科学
肿瘤细胞
作者
Nirupama Mulherkar,David T. Scadden
标识
DOI：10.1016/j.beha.2021.101328
摘要
Acute myeloid leukemia (AML) continues to be associated with relapse and resistance to chemotherapy. The bone marrow microenvironment in AML has been shown to regulate responsiveness to chemotherapy and to support disease progression. This review summarizes some recent experimental insights into the crucial role of the bone marrow microenvironment in AML and persistence after chemotherapy.
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