Objective: This essay aims at exploring the evaluation of repeat colonoscopy and endoscopic therapy for delayed post-polypectomy hemorrhage. Methods: Nine patients who presented with active rectal bleeding 24 hours to 12 days after snare resection of colon polyp were given repeat colonoscopy and endoscopic therapy. Results: Repeat colonoscopy identified the bleeding site, and injection therapy, electrocautery or combinations of injection therapy with electrocautery led to cessation of hemorrhage. No complications resulted from repeat colonoscopy and endoscopic therapy. Conclusions: Repeat colonoscopy and endoscopic therapy is feasible, effective, and safe in patients with active delayed post-polypectomy hemorrhage.