Mucoadhesive Buccal Drug Delivery System - An Unique Novel Drug Delivery System of the Modern Era

With the current emergence of Novel Drug Delivery Systems, mucoadhesive drug delivery systems march outs its significance as an unique novel drug delivery system in the present scenario. The term mucoadhesion in a simpler manner signifies the adhesion of two materials with each other where one of the materials is the mucosal surface. Certain investigations are on progress to find out an alternative route which can by-pass hepatic metabolism, reduce dose frequencies and prolong the drug action. In those cases, delivery of drugs through buccal cavity can be brought up into the real picture. The dosage forms of mucoadhesive drug delivery system include solids, semisolids and transparent drug loaded films. This when comes into contact with the buccal mucous membrane, drug tends to release at a sustained and controlled manner through the blood capillaries associated in the buccal cavity assuring maximum bioavailability and thereby increases the ease of drug administration, by-passes hepatic portal systems and gastrointestinal tract, increase in therapeutic efficacy, improves patient compliance and reduction in dose frequencies.