医学
磁共振成像
磁共振弥散成像
接收机工作特性
阶段(地层学)
淋巴
有效扩散系数
淋巴结
曼惠特尼U检验
转移
宫颈癌
逻辑回归
放射科
核医学
颈淋巴结
癌症
病理
内科学
生物
古生物学
作者
Xiaomiao Zhang,Yue Dong,Qingling Song,Yanmei Zhu,Huiting Pang,Yahong Luo,Tao Yu,Fan Liu,Yan Guo
出处
期刊:Journal of Computer Assisted Tomography
[Ovid Technologies (Wolters Kluwer)]
日期:2020-08-25
卷期号:44 (5): 750-758
被引量:7
标识
DOI:10.1097/rct.0000000000001084
摘要
Objective The aim of this study was to investigate the value of multiparametric magnetic resonance imaging (MRI) in demonstrating the metastatic potential of primary tumor and differentiating metastatic lymph nodes (MLNs) from nonmetastatic lymph nodes (non-MLNs) in stage IB1–IIA1 cervical cancer. Methods Fifty-seven stage IB1–IIA1 subjects were included. The apparent diffusion coefficient (ADC) values and dynamic contrast-enhanced MRI (DCE-MRI) parameters of primary tumors and lymph nodes and the conventional imaging features of the lymph nodes were measured and analyzed. Mann-Whitney test and χ 2 test were used to analyze statistically significant parameters, logistic regression was used for multivariate analysis, and receiver operating characteristic analysis was used to compare the diagnostic performance of the MLNs. Results Nineteen subjects had lymph node metastasis. A total of 94 lymph nodes were evaluated, including 30 MLNs and 64 non-MLNs. There were no significant difference in ADC and DCE-MRI parameters between metastatic and nonmetastatic primary tumors. The heterogeneous signal was more commonly seen in MLNs than in non-MLNs ( P = 0.001). The values of ADC mean , ADC min , and ADC max of MLNs were lower than those of non-MLNs ( P < 0.001). The values of short-axis diameter, K trans , K ep , and V e of MLNs were higher than those of non-MLNs ( P < 0.05). Compared with individual MRI parameters, the combined evaluation of short-axis diameter, ADC mean , and K trans showed the highest area under the curve of 0.930. Conclusions Diffusion-weighted imaging and DCE-MRI could not demonstrate the metastatic potential of primary tumor in stage IB1–IIA1 cervical cancer. Compared with individual MRI parameters, the combination of multiparametric MRI could improve the diagnostic performance of lymph node metastasis.
科研通智能强力驱动
Strongly Powered by AbleSci AI