Distinct bacterial facial cutaneous microbiota composition in adolescents with acne vulgaris: a population-based cross-sectional observational study

Our findings reveal distinct facial microbiota compositions in adolescents with acne, identifying C. granulosum, C. acnes, and S. epidermidis as key microbial signature. This study suggests a significant clinical relevance for C. granulosum in acne pathology and a potential protective role for Streptococcus in acne-free skin. These results underscore the importance of representative study populations in microbiome research and provide important methodological and technical insights for future investigations.