Practicable regiospecific bifunctionalization on the secondary face of α- and β-cyclodextrins

Practicable regiospecific bifunctionalization onto the A,B-secondary hydroxyl face of α- and β-cyclodextrins, such as diepoxidation and diamination, has been made possible by staple-disulfonation with benzophenone-3,3′-disulfonyl imidazole and molecular sieves in DMF.