Efficacy and safety of acupuncture and moxibustion combined with the external application of traditional Chinese medicine in the treatment of primary liver cancer: A protocol for systematic review and meta-analysis

Review question / Objective: The aim of this systematic review is to valuate the efficacy and safety of acupuncture and moxibustion combined with the external application of traditional Chinese medicine in the treatment of primary liver cancer.To this end, the proposed systematic review will address the following question: Which is the best choice to effective in improving The short-term curative effect is effective, the quality of life is stable, and the survival rate of patients is six months/one year in patients with primary liver cancer, acupuncture combined with external application of traditional Chinese medicine or the best supportive treatment?Information sources: We will search the following databases: PubMed, Web of Science, GCBI, Embase, OVID, AMED, Cochrane Library, CNKI, VIP, CBM and Wanfang.At the same time, we will manually search all reference lists from relevant systematic reviews to find other eligible studies.We will exclude all conference records, reviews, meta-analyses, newspapers, guides, letters and other documents.When the full text or the required information in the analysis process was missing, the author of the studies was contacted for data.