Visible-light photocatalyzed radical dipolar annulations for diastereoselective synthesis of pyrrolo[2,1- a ] isoquinoline-fused benzosulfolane skeletons

We report a visible-light photocatalyzed radical 1,3-dipolar cycloaddition between benzo[ b ]thiophene sulfones and tetrahydroisoquinolines, providing an approach for the concise synthesis of pseudo-natural inspired fused pentacyclic skeletons.