Antiviral activity of aucubin against hepatitis B virus replication

Aucubin, an iridoid glycoside was found to suppress hepatitis B virus DNA replication in vitro in a 2.2.15 cell culture system. Aucubin itself did not exhibit antiviral activity, but it showed significant activity when preincubated with . Aucubin possesses no cytotoxicity at a broad range of concentrations in vitro. © 1997 John Wiley & Sons, Ltd.