Tip 2 diyabetli hastalarda mukokutanöz fungal infeksiyonlar için risk faktörleri

Background and Design: Mucocutaneous fungal infections are common in patients with diabetes mellitus (DM).However, fungal infections do not develop in all patients with DM.In this study, we aimed to determine the risk factors for mucocutaneous fungal infections in patients with Type 2 DM. Materials and Methods: A total of 302 Type 2 DM patients with mucocutaneous fungal infections and 326 Type 2 DM patients without mucocutaneous fungal infections were enrolled.Demographic and clinical features, HbA1c levels, DM durations, body mass indexes (BMIs) and DM-related complications were compared between the groups and risk factors for developing mucocutaneous fungal infections were determined.Results: Of the 302 patients with mucocutaneous fungal infections, 81.2% (n=245) had dermatophytosis, 16.9% (n=51) had candida infections, and 2.0% (n=6) had pityriasis versicolor.Frequency of male gender, diabetic nephropathy, neuropathy and retinopathy; DM durations and age of patients were all significantly higher in diabetic patients with fungal infections than in patients without fungal infections (all p<0.05).Male gender, age ≥ 50 years, nephropathy and neuropathy were independently associated with fungal infection in Type 2 DM patients.In subgroup analyses, independent risk factors for dermatophytosis were male gender, age ≥ 50 years, DM duration ≥ 5 years, and nephropathy.For candidiasis, these factors were BMI≥30 and neuropathy.Conclusion: Elderly, male gender, diabetic neuropathy and nephropathy are closely associated with mucocutaneous infections in patients with Type 2 DM.(Turkderm 2014; 48: 87-91) Key Words: Diabetes mellitus