Digital transformation is recognized as an increasingly essential facilitator to improve the efficiency and performance of organizations through utilizing digital technologies to impel organizational change, especially after the occurrence of pandemic.While companies and governments are heavily investing in the digital development, the performance on invest seems not satisfactory.Extant researches indicate that digital capability and mindset have been the major obstacles for companies to combine the digital technologies into current business process and achieve a satisfactory result of implementing digital transformation.Though there are abundant sophisticated studies on technology acceptance at individual level, given the dynamic nature of digital transformation, it is necessary to investigate the factors that would influence users to transit mindset to be digital and embrace the digital technologies in the everchanging context.Hence, this paper endeavors to fill the gap mentioned above through investigating how to engage business process owners to facilitate the performance of digital transformation in an agile manner through theoretical research framework with secondary data support.From a theoretical view, this research extends UTAUT model from the aspect of user attributes in individual level contextual factors by combining Neurological levels.From a managerial perspective, it applies agile management in digital transformation from the perspective of business process owners.The result shows that in order to achieve satisfactory performance of the digital transformation, the organizations need to facilitate an agile environment for business process owners to develop digital mindset and digital capabilities following neurological levels to speed in routinizing and integrating new technologies in to existing business process, and it is imperative for management to encourage process owners to treat change as constant and to be agilely adapt to the dynamic nature of continual digital transformation.