糖尿病酮症酸中毒
医学
气体分析呼吸
呼气
糖尿病
内科学
呼出的空气
重症监护医学
麻醉
内分泌学
解剖
作者
Qing Zhou,Qiannan Wang,Bin Chen,Yi Han,Lei Cheng,Yaqian Shen,Panpan Hao,Zhong-Wen Zhang
出处
期刊:Journal of Breath Research
[IOP Publishing]
日期:2019-09-06
卷期号:13 (4): 046012-046012
被引量:5
标识
DOI:10.1088/1752-7163/ab285a
摘要
Breath analysis is used to detect the composition of exhaled gas. As a quick and non-invasive detection method, breath analysis provides deep insights into the progression of various kinds of diseases, especially those with metabolism disorders. Abundant information on volatile compounds in diabetic patients has been studied in numerous articles in the literature. However, exhaled gas in diabetic patients can be altered by various complications. So far, little attention has been paid to this alteration. In our paper, we found that under air pollution conditions, diabetic patients exhale more nitric oxide. Diabetic patients with heart failure exhale more acetone than those without heart failure. After 13C-labeled glucose intake, patients infected with Helicobacter pylori exhaled more 13C and less 18O than those without infection. Exhalation with chronic kidney disease changes volatile organic compounds on a large scale. Diabetic patients with ketoacidosis exhale more acetone than those without ketoacidosis. Some specific volatile organic compounds also emanate from diabetic feet. By monitoring breath frequency, diabetic patients with obstructive sleep apnea syndrome exhibit a unique breath pattern and rhythm as compared with other diabetic patients, and sleep apnea is prevalent among diabetic patients. In addition to clinical findings, we analyzed the underlying mechanisms at the levels of molecules, cells and whole bodies, and provided suggestions for further studies.
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