允许的
胰腺癌
成纤维细胞
癌症研究
肿瘤细胞
生物
癌症
癌相关成纤维细胞
癌细胞
肿瘤微环境
医学
细胞生长
胰腺
细胞
内科学
免疫学
细胞生物学
癌变
细胞培养
遗传学
作者
Emily Kay,Sara Zanivan
出处
期刊:Cancer Cell
[Elsevier]
日期:2021-09-13
卷期号:39 (9): 1175-1177
标识
DOI:10.1016/j.ccell.2021.07.022
摘要
Fibroblasts are a major non-neoplastic component of solid tumors, yet it is unclear whether they promote or oppose cancer. In this issue of Cancer Cell, Hutton et al. report two distinct fibroblast subpopulations that are defined by a single marker, one subpopulation that is tumor permissive and the other that is tumor suppressive and supports anti-tumor immunity.
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