Synthesis and activity test as antioxidant of two hydroxydibenzalacetones

Synthesis and antioxidant activity test of two hydroxydibenzalacetones have been conducted. 2,2,-Dihydroxydibenzalacetones and 3,3,-dihydroxydibenza--lacetones were synthesized by crossed aldol condensation in base condition with water-ethanol solvent from 2-hydroxybenzaIdehyde and 3-hydrojvhenzaldehyde as raw material respectively. The synthesis reaction was conducted in ice bath environment under stirring and followed by precipitation and purification by recrystalization with methanol-water as solvent. After filtration, 60.15% blackish green crystalline of 2,2, -dihydroxydibenzalacetone and 78.94% yellow crystalline of 3,3'dihydroxydibenzalacetone were obtained. The ICM of two compounds were 791.62 and 196.56 iig/mL respectively.