Exploring the entropy-driven amplification reaction and trans-cleavage activity of CRISPR-Cas12a for the development of an electrochemiluminescence biosensor for the detection of the SARS-CoV-2 RdRp gene in real samples and environmental surveillance

An ECL biosensor based on entropy-driven amplification and CRISPR-Cas12a shear for the detection of the SARS-CoV-2 RdRp gene in environmental surveillance was reported.