Objectives: To find out association of length and muscle strength of thumb with thumb pain among manual physicaltherapists.Material and Methods: A Self-administered questionnaire based cross-sectional survey was undertaken to detect theassociation of thumb pain among 74 physical therapists at different hospitals and clinics of Lahore, Pakistan from Jan2017 to June 2017. The length of the thumb was measured using inch tape. The push force of thumb was measuredusing pinch gauge. The data was collected and analyzed statistically by SPSS software 20.Results: Odds greater than 1 (>1) means the chances of thumb pain is greater as compared to no thumb pain.Variables like Length of thumb, Force applied by right thumb & both thumbs on gauge have high odds and they havehigh effect on thumb pain. Force applied by left thumb below 1 (<1) odds is having less contribution in thumb pain.Conclusion: Length of the thumb, force of right and both thumb, are associated with thumb pain. Other variables andforce of left thumb are not associated with thumb pain.