1H-MRS of the anterior cingulate cortex in obsessive-compulsive disorder: glutamatergic abnormalities in ACC – controlled study

p¼0.039).The HC also displayed a lower activity of the bilateral anterior cingulate cortex (ACC) than patients with BN and ACC activity was negatively related to food delay discounting rates in patients with BN.In patients with AUD but not in HC, there were higher alcohol delay discounting rates (p<0.001).Patients with AUD also had a lower activity of the bilateral supplementary motor area (SMA) compared to before the MIST and this was related to higher alcohol delay discounting rates. Conclusion:The results of this study show that HC prefer more immediately available food when stressed, and that this could be related to a change in ACC activity.However, this was not the case in patients with BN which could be linked to a tendency to restrict food intake when stressed.The findings also show that patients with AUD, but not HC, prefer more immediately available alcohol when stressed, and that this could be related to a change in activity of the SMA.