Adverse Life Events Across the Life Course and the Risk of New‐Onset Cardiovascular‐Kidney‐Metabolic Multimorbidity in Middle‐Aged and Older Adults: Longitudinal Evidence From CHARLS

Life course adversity, particularly experiences involving violence or deprivation, substantially increases the risk of CKM multimorbidity in later life. These findings emphasize the importance of integrated prevention addressing psychosocial and mental health factors. Key limitations include deviation from American Heart Association-recommended CKM definitions due to incomplete obesity data and self-reported chronic kidney disease, which may have led to misclassification.