Palladium catalyzed C–H bond acetoxylation: isoxazolinyl as a directing group

Pd(OAc)₂-catalyzed acetoxylations of 3-aryl or 3-alkyl groups mounted on a 2-isoxazoline ring were studied. Substituent effect on reactivity and regioselectivity was examined. The acetoxylation was applied to the synthesis of useful intermediates.