代谢组学
蓝图
仿形(计算机编程)
计算生物学
生物
生物信息学
数据科学
医学
计算机科学
工程类
机械工程
操作系统
作者
Christopher B. Newgard
标识
DOI:10.1016/j.cmet.2016.09.018
摘要
Metabolomics, or the comprehensive profiling of small molecule metabolites in cells, tissues, or whole organisms, has undergone a rapid technological evolution in the past two decades. These advances have led to the application of metabolomics to defining predictive biomarkers for incident cardiometabolic diseases and, increasingly, as a blueprint for understanding those diseases’ pathophysiologic mechanisms. Progress in this area and challenges for the future are reviewed here. Metabolomics, or the comprehensive profiling of small molecule metabolites in cells, tissues, or whole organisms, has undergone a rapid technological evolution in the past two decades. These advances have led to the application of metabolomics to defining predictive biomarkers for incident cardiometabolic diseases and, increasingly, as a blueprint for understanding those diseases’ pathophysiologic mechanisms. Progress in this area and challenges for the future are reviewed here.
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