米多司他林
药理学
医学
药代动力学
CYP2B6型
CYP2C8
加药
药物相互作用
CYP3A4型
内科学
细胞色素P450
白血病
新陈代谢
作者
Romain Séchaud,Helen Gu,Gholamreza Rahmanzadeh,Amanda Taylor,Ovidiu Chiparus,Gopal Krishna Sharma,Astrid Breitschaft,Hans D. Menssen
标识
DOI：10.1007/s00280-023-04635-3
摘要
Midostaurin neither inhibits nor induces CYP3A4 and CYP2C8, and weakly induces CYP2B6. Midostaurin at steady state has no clinically relevant PK interaction on hormonal contraceptives. All treatments were well tolerated.
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