Hong Guo ginseng Guo (HGGG) Protects against kidney injury in Diabetic Nephropathy by Inhibiting NLRP3 Inflammasome and Regulating Intestinal Flora

Diabetic nephropathy (DN) is one of the most serious complications of diabetes which leads to end-stage renal failure and approximately one-third of patients need dialysis. There is still a lack of effective and specific treatment for DN. Searching new drugs from natural foods is an alternative approach to treat diabetes and its complications. Hong Guo Ginseng Guo (HGGG), a berry with palatability and nutritional benefits, has exhibited medicinal properties to mitigate the progression of DN.