Assessment of seven insulin resistance surrogate indexes for predicting cardiometabolic multimorbidity among Chinese middle-aged and older adults: a national prospective cohort study

All seven insulin resistance surrogate indexes independently demonstrated elevated CMM risk. In the context of Chinese middle-aged and elderly cohorts, eGDR demonstrated a notable predictive capacity for CMM. ROC-derived cut-offs (eGDR < 7.64) are utilised for identifying high-risk individuals requiring intervention. Spline-derived thresholds (eGDR = 11.82) serve as therapeutic targets for risk reduction.