Evaluation in vitro of Huperzine A Gastrointestinal Bioadhesive Tablets

Studying on bioadhesion of Huperzine A gastrointestinal bioadhesive tablets is the main aim. The bioadhesive force was evaluated by a self-made apparatus, and compared the force between different bioadhesive tablets and gastric or intestinal mucosa. In the same time, the content of swelling and expansion of tablets were also studied. The findings show the bioadhesion force of tablets on gastric mucosa is far smaller than that on intestinal, and the force of bioadhesive tablets is larger than that of the blank.