酪氨酸酶
五加科
人参
苯丙素
对香豆酸
化学
精梳科
抑制性突触后电位
传统医学
生物化学
酶
植物
生物
生物合成
医学
阿魏酸
替代医学
病理
神经科学
作者
Jeong‐Yeon Lim,Kyoko Ishiguro,Isao Kubo
标识
DOI:10.1002/(sici)1099-1573(199908/09)13:5<371::aid-ptr453>3.0.co;2-l
摘要
By bioassay-guided fractionation using mushroom tyrosinase, p-coumaric acid was characterized as the principal tyrosinase inhibitor from the fresh leaves of Panax ginseng (Araliaceae). It inhibited the oxidation of L-tyrosine more strongly than that of L-3,4-dihydroxyphenylalanine (L-DOPA) by this enzyme. On the basis of this finding, various related phenylpropanoid analogues were also tested in order to gain new insights into their structural criteria. Copyright © 1999 John Wiley & Sons, Ltd.
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