脑电图
镇静
胶质瘤
医学
异丙酚
麻醉
颞叶
额叶
心理学
癫痫
精神科
癌症研究
作者
Wanning Yang,Xinxin Wang,Haiyang Liu,Muhan Li,Xiaoyuan Liu,Nan Lin,Li Hu,Ruquan Han
标识
DOI:10.1016/j.neulet.2023.137284
摘要
Gliomas are the most common primary intracranial malignant tumors. Some of these patients exhibit previously clinically undetected neurological deficits after sedation. The absence of neurophysiological evidence for this phenomenon limits the use of time-sensitive monitoring methods. The study aims to compare differences between glioma patients under sedation and those without intracranial lesions by comparing their EEG features. Twenty-one patients without intracranial tumors and 21 with frontal lobe supratentorial gliomas were enrolled. The EEG power spectrum of the glioma group was comparable to that of the control group for both sides of the brain (P > 0.05 for all frequencies). Compared with those without intracranial lesions, the weighted phase lag index (wPLI) in the alpha and beta bands on the non-occupied side decreased. Glioma patients had weaker functional connectivity during sedation than patients without intracranial lesions, manifesting as reduced functional connectivity on the non-occupied side.
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