Visual outcomes after implantation of a nondiffractive EDOF intraocular lens in patients with early dry macular degeneration

Purpose: To evaluate visual outcomes after implantation of a nondiffractive extended depth-of-focus (EDOF) intraocular lens (IOL) in patients with early age-related dry macular degeneration (AMD). Setting: Iladevi Cataract & IOL Research Centre, Ahmedabad, India. Design: Prospective, interventional series. Methods: Patients undergoing cataract surgery with the EDOF AcrySof Vivity IOL and having early dry AMD were included. Primary outcome measures were monocular unaided and corrected distance visual acuity (UDVA, CDVA) 3 months postoperatively. Secondary outcome measures were monocular unaided and distance-corrected intermediate (UIVA, DCIVA) (66 cm) and near (UNVA, DCNVA) (40 cm) visual acuity as well as mesopic contrast sensitivity (CS). Results: 40 eyes (40 patients) with a mean age of 68.5 ± 8.38 (SD) years were included. UDVA and CDVA at 3-month follow-up were 0.12 ± 0.07 and 0.10 ± 0.10 (SD) logMAR. UIVA and DCIVA were 0.25 ± 0.09 and 0.12 ± 0.09 logMAR. UNVA and DCNVA were 0.23 ± 0.10 and 0.19 ± 0.15 logMAR. Mesopic CS values without glare were 1.50 ± 0.10, 1.69 ± 0.26, 1.40 ± 0.30, and 0.84 ± 0.5 units at 3, 6, 12, and 18 cycles per degree. Mesopic CS with glare was 1.53 ± 0.16, 1.63 ± 0.21, 1.21 ± 0.45, and 0.75 ± 0.42 units. Conclusions: The AcrySof Vivity IOL gave very good distance visual acuity with improved intermediate and near visual acuity without significant compromise in CS in eyes with early dry AMD.