Visual Outcomes following implantation of a non-diffractive extended depth of focus Intraocular Lens in patients with early dry macular degeneration

To evaluate visual outcomes after implantation of a nondiffractive extended depth-of-focus (EDOF) intraocular lens (IOL) in patients with early age-related dry macular degeneration (AMD). Iladevi Cataract & IOL Research Centre, Ahmedabad, India. Prospective, interventional series. Patients undergoing cataract surgery with the EDOF AcrySof Vivity IOL and having early dry AMD were included. Primary outcome measures were monocular unaided and corrected distance visual acuity (UDVA, CDVA) 3 months postoperatively. Secondary outcome measures were monocular unaided and distance-corrected intermediate (UIVA, DCIVA) (66 cm) and near (UNVA, DCNVA) (40 cm) visual acuity as well as mesopic contrast sensitivity (CS). 40 eyes (40 patients) with a mean age of 68.5 ± 8.38 (SD) years were included. UDVA and CDVA at 3-month follow-up were 0.12 ± 0.07 and 0.10 ± 0.10 (SD) logMAR. UIVA and DCIVA were 0.25 ± 0.09 and 0.12 ± 0.09 logMAR. UNVA and DCNVA were 0.23 ± 0.10 and 0.19 ± 0.15 logMAR. Mesopic CS values without glare were 1.50 ± 0.10, 1.69 ± 0.26, 1.40 ± 0.30, and 0.84 ± 0.5 units at 3, 6, 12, and 18 cycles per degree. Mesopic CS with glare was 1.53 ± 0.16, 1.63 ± 0.21, 1.21 ± 0.45, and 0.75 ± 0.42 units. The AcrySof Vivity IOL gave very good distance visual acuity with improved intermediate and near visual acuity without significant compromise in CS in eyes with early dry AMD.