Label‐Free Colorimetric Detection of Single Nucleotide Polymorphism by Using Single‐Walled Carbon Nanotube Intrinsic Peroxidase‐Like Activity

(Figure Presented) SWNTs possess intrinsic peroxidaselike activity, catalyzing the reaction of peroxidase substrate 3, 3, 5, 5-tetramethylbenzidene (TMB) in the presence of H2O2 to produce a color reaction. Here SWNTs have been used for label-free colorimetric detection of disease-associated single-nucleotide polymorphism with a direct detection limit of 1 nM. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA.