The Influence of Radiotherapy and Chemotherapy on Platelet Parameters in Tumor Patients and Its Significance

Objective:To study the changes of platelet parameter in tumor patients before or after radiotherapy and chemotherapy and the clinic significance.Methods: 31 cases of tumor patients before or after radiotherapy and chemotherapy were selected and their platelet parameters(PLT,PCT,MPV,DPW,P-LCR) were measured by the sysmex SF-3000 complete automatic hemanalysis, then compared with control group.Results: There was no signficant difference between the two groups in the platelet parameters before radiotherapy and chemotherapy(P0.05).The levels of PLT,PCT,MPV,P-LCR in tumor patients after radiotherapy and chemotherapy were significantly lower than that before radiotherapy and chemotherapy(P0.01或P0.05),but PDW is no different(P0.05).Conclusion:Determine of platelet parameters of tumor patients before or after radiotherapy and chemotherapy is of certain clinical significance for observation of the status of their marrow restrained and estimate of state of illness.