Relationship between the corneal central thickness and the retinal nerve fiber layer thickness in the patients with ocular hypertension and normal people

Objective To research the relationship between the corneal central thickness(CCT) and the retinal nerve fiber layer(RNFL) thickness in the patients with ocular hypertension.Methods Intraocular pressure(IOP) and central corneal thickness were measured to gain the corrected IOPs in 180 eyes with ocular hypertension.These patients were examined with OCT and GDx-VCC in the detection of retinal nerve fiber layer thickness.Otherwise the same data were acquired in 180 normal eyes to be compared.The data were statistically analyzed by t-test.Results In the group of ocular hypertension,the average central corneal thickness was 536.14±35.99(433～609)μm.In the group of normal ocular tension,the average central corneal thickness was 516.68±38.27(368～598)μm.All RNFL parameters showed were statistically significant lower in the patients of ocular hypertension group than those of the normal people.Conclusion There was significant difference between the OCT and GDx-VCC but they have significant plus correlation.In the patients of intraocular hypertension,the thinner of the CCT,the lower of the RNFL,There are positive correlation in the CCT and RNFL.