Transcutaneous electrical acupoint stimulation reduces postoperative patients’ length of stay and hospitalization costs: A systematic review and meta-analysis

Objective: To study the effects of transcutaneous electrical acupoint stimulation (TEAS) on length of stay (LOS) and hospitalization costs in postoperative inpatients. Methods: Two researchers collectively searched PubMed, Embase, Cochrane Library, China Network Knowledge Infrastructure and Wanfang Database. The search time was set from the beginning to April 25, 2023, to identify randomized controlled trials articles that met the criteria. Statistical analyses were performed using the Stata software (version 16.0). The risk of bias was assessed using the Cochrane risk-of-bias tool, and publication bias was evaluated using a funnel plot and Egger’s test. The quality of evidence was assessed according to the Grading of Recommendations Assessment, Development, and Evaluation approach. Results: Thirty-four randomized controlled trials were included. The main results showed that TEAS reduced hospitalization costs (standardized mean difference (SMD)=−1.92; 95% confidence interval (CI) −3.40, −0.43), LOS (SMD=−1.00; 95% CI −1.30, −0.70) and postoperative LOS (SMD=−0.70; 95% CI −0.91, −0.49) in postoperative patients. Subgroup analyses further revealed that TEAS was effective in reducing both the overall and postoperative LOS in patients undergoing multiple surgical procedures. It is worth noting that the observed heterogeneity in the results may be attributed to variations in surgical procedures, stimulation frequencies, and stimulation points utilized in different trials. Conclusions: TEAS can help postoperative patients reduce their LOS and hospitalization cost. However, considering the bias identified and heterogeneity, the results of this review should be interpreted with caution.