血管生成
氧化应激
叙述性评论
癌症
细胞凋亡
抗氧化剂
疾病
药理学
癌症研究
癌细胞
医学
生物信息学
生物
生物化学
内科学
重症监护医学
作者
Kuldeep Singh,Jeetendra Kumar Gupta,Shivendra Kumar,Talever Singh
出处
期刊:Current Bioactive Compounds
[Bentham Science Publishers]
日期:2023-09-11
卷期号:20 (2)
被引量:2
标识
DOI:10.2174/1573407219666230907115809
摘要
Abstract: Bioactive peptides derived from soybeans have recently been identified as having potential health benefits for preventing and curing cancer and cardiovascular disorders. This narrative review focuses on the potential role of these peptides in such conditions and the possible mechanisms by which they may act. Soybean-derived bioactive peptides have been found to possess antitumor, antioxidant, anti-inflammatory, and cholesterol-lowering effects. Animal and in vitro studies have demonstrated that these peptides can modulate multiple signaling pathways, including those involved in the regulation of apoptosis, angiogenesis, and cell proliferation. Furthermore, they may protect against oxidative stress and lipid accumulation, which are associated with cancer and cardiovascular diseases. Also, soybean peptides have been shown to stop enzymes from breaking down cancer-causing chemicals and reduce the production of pro-inflammatory cytokines, which are linked to a higher risk of heart disease. The potential of soybean-derived peptides as a therapeutic tool in cancer and cardiovascular diseases is promising. However, further studies are needed to elucidate their mechanisms of action and assess their safety and efficacy in clinical settings.
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