纳米载体
透皮
生物相容性材料
药物输送
纳米技术
药品
毒品携带者
计算机科学
材料科学
药理学
生物医学工程
医学
作者
Ujjwal Kumar Biswas,Shreeja Sen,Susrita Sharma,Mohana Paul,Amit Kumar Nayak,Anindya Bose,Anindya Bose
标识
DOI:10.2174/0115672018335655241015062436
摘要
Nanostructured lipid carriers (NLCs) are lipidic nanocarriers that recover the permanency and capacity of drug payloads. NLCs are well-known as second-generation lipid nanocarriers with an unstructured matrix, presenting potentially advantageous nanocarrier systems with marketable opportunities because of reproducible production methodologies and biocompatible lipidic excipients. These (NLCs) are now recognized as a very promising nanocarrier structure for the efficient delivery of drugs via different administration routes. In recent years, several NLC-based gels have been developed and evaluated for topical delivery of many drugs and other therapeutic agents. This review article presents an overview of NLC-based topical gels investigated to deliver drugs via ocular, dermal, and transdermal routes. In addition, the classification, manufacturing, characterizations, advantages, and disadvantages of NLCs are addressed in this article. We also discussed different evaluations of NLC-based topical gels.
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